Redefine and simplify your biologics manufacturing processes. 3M’s anion exchange chromatography, single-use, hybrid purifier is designed for bringing chromatography in upstream processing for particle control, reduce DNA and host cell proteins.
3M’s hybrid purifier incorporates anion exchange chromatography and membrane filtration to provide chromatographic clarification and mechanical separation by size. At the heart of the hybrid solution is an anion exchange hydrogel media based on a non-woven material support that carries quaternary ammonium (Q) functionality. It works by using anion exchange chromatography in a single-use device.
The anion exchange chromatography of the functional nonwoven provides substantial reduction of soluble impurities and of insoluble particles below 0.1 microns for superior turbidity reduction. Users may see substantial reductions of DNA and of host cell proteins (HCP). Integrating the purifier at the clarification stage may reduce the total cost of ownership for the monoclonal antibodies (mAb) purification process.
Our experts will work with you to help find the optimal 3M purification and filtration solution for your application and to test our products within your process. We also provide trial data when we work with you to demonstrate product in-use.
A 3M representative will be in contact with you shortly or you can call us on 1300 345 837 (option 3).
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From anion exchange chromatographic clarification of cell culture for providing chromatographic protection to chromatographic column for mAb and other recombinant proteins processing.
From chromatographic reduction of soluble impurity to bioburden reduction, 3M anion exchange chromatography technologies deliver robust scalable solutions for cell culture applications in biopharmaceutical manufacturing.
3M chromatography single use hybrid purifiers designed for soluble and insoluble impurities reduction using anion exchange chromatography in clarification of mAbs and other recombinant proteins. Designed for DNA reduction, 3M™ Emphaze™ AEX Hybrid Purifier is a multi-mechanism single-use device containing anion exchange chromatography media integrated with a fine particle, bioburden reduction membrane.
The 3M Emphaze AEX Hybrid Purifier is a combination of two types of media (anion exchange chromatographic functional nonwoven and membrane) that work together to provide unsurpassed product purity when using a single unit operation. The integral combination of the 0.2 micron rated membrane and anion exchange nonwoven provides robust reduction of insoluble particles well below 0.1 micron.